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041 _afre
042 _adc
100 1 0 _aSmirnov, Artem
_eauthor
700 1 0 _a Anemona, Lucia
_eauthor
700 1 0 _a Montanaro, Manuela
_eauthor
700 1 0 _a Mauriello, Alessandro
_eauthor
700 1 0 _a Annicchiarico-Petruzzelli, Margherita
_eauthor
700 1 0 _a Campione, Elena
_eauthor
700 1 0 _a Melino, Gerry
_eauthor
700 1 0 _a Candi, Eleonora
_eauthor
245 0 0 _aTransglutaminase 3 is expressed in basal cell carcinoma of the skin
260 _c2019.
500 _a75
520 _aBackgroundTransglutaminase 3 (TG3) belongs to a family of Ca2+-dependent enzymes which catalyse protein crosslinking. TG3 is important for proper development of the skin and hair shaft, and knock-out mice for the Tgm3 gene are sensitive to UVB-induced photodamage due to aberrations in cornified envelope formation. Loss of TG3 is reported in head and neck and oesophageal squamous cell carcinoma, yet, its expression in skin cancer has not been studied.
690 _askin cancer
690 _asquamous cell carcinoma
690 _amelanoma
690 _atransglutaminase 3
690 _akeratinocytes
690 _abasal cell carcinoma
786 0 _nEuropean Journal of Dermatology | 29 | 5 | 2019-09-01 | p. 477-483 | 1167-1122
856 4 1 _uhttps://shs.cairn.info/revue-european-journal-of-dermatology-2019-5-page-477?lang=en&redirect-ssocas=7080
999 _c602178
_d602178