TY  - BOOK
AU  - Grand,François
AU  -  Blanc-Jouvan,Florence
AU  -  Delassasseigne,Céline
AU  -  Galinat,Hubert
AU  -  Roy,Pierre-Marie
AU  -  Talon,Laurie
AU  -  Toussaint-Hacquard,Marie
AU  -  Macchi,Laurent
TI  - Point-of-care testing for D-dimer in the exclusion of venous thromboembolism: A critical analysis
PY  - 2023///.
							
N1  - 52
N2  - Point-of-care testing (POCT) for D-dimer is an alternative to ­laboratory testing for the exclusion of venous thromboembolism (VTE). This critical review by the “extracorporeal circulation (ECC) and point-of-care testing” working group of the Société Française de Thrombose et d’Hémostase (French Society of Thrombosis and Hemostasis) aims to present the characteristics of six POCT D-dimer assays available in France in 2023. The article highlights the need to define VTE ­exclusion cutoffs specific to each technique and validated by clinical studies. There is insufficient data to validate the use of cutoffs suggested by manufacturers and age-adjusted thresholds. The article discusses the role of laboratories in justifying and prescribing POCT for D-dimer, according to objective criteria, such as the availability and turnaround time of classical laboratory tests. Rational prescribing should also be encouraged, limited to patients with a low risk of VTE, following an assessment of clinical probability according to national and international guidelines
UR  - https://shs.cairn.info/journal-annales-de-biologie-clinique-2023-5-page-461?lang=en&redirect-ssocas=7080
ER  -