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Background — Religion may play a major role for medical students with regard to their own sexuality, as well as to their approach to sexual counseling in future. We aimed to examine sexual function, attitudes, and behaviors in male medical students, and to investigate the relationship between sexuality and dimensions of religiosity. Method — This was a cross-sectional study. A total of 146 male medical students (mean age of 22.2 years) were surveyed using the International Index of Erectile Function and the Arabic Religiosity Scale. Results — Students who had higher religiosity levels had fewer sexual partners, tended to believe that a man should have sex with only one partner and only after marriage, were more likely to regret their first sexual experience “very much,” and were less likely to use pornography. After controlling for confounding variables, only alcohol use and perception of first sexual experiences were found to contribute significantly to students’ sexual function, while overall religiosity was not found to contribute to sexual function. Conclusion — Making young medical students aware of their own attitudes towards sexuality and of the fact that these attitudes could be shaped by preconceived religious beliefs can represent a first step toward successfully preparing students for sexual counseling in future and shaping their attitudes toward patients.