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Psychological symptoms frequently seen in palliative care are anxiety, depression, and a wish for death. These symptoms are often a source of distress and great, but unknown psychological suffering; yet, they are considered as a natural process in any terminally ill patients, and as a consequence they are often under-diagnosed and under-treated. Recognition of depression symptoms must therefore be integrated into routine care, and all team members have an important role in detecting these symptoms. More comprehensive training based on key skills should complement the screening. Such issues will substantially improve efficient management, in order to better assist depressive patients and their relatives during the process of bereavement and death.