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As in most western countries, feminisation has probably been the most significant change occurring in the Quebec labour market in the last twenty years. The rise of female-headed single-parent families contributes to the resulting need for women to be “breadwinners”. However, there still is a strong wage differential between men and women, and part of it may be due to the spatial conditions that affect access to employment. In this paper, we examine the relations between spatial mobility of women, job accessibility and occupational mobility over the last twenty years in the Quebec urban region. Results show that better job accessibility, longer female work commutes and better car access had a significant effect on the female employment rate and on the upward occupational mobility of women between 1977 and 1996.